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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
1.82
Human Site:
S1303
Identified Species:
3.08
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S1303
E
P
E
T
T
D
A
S
H
P
S
V
P
P
E
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
P1136
V
P
L
P
P
P
E
P
P
A
G
P
P
A
P
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
A70
S
Q
F
P
P
S
G
A
R
E
V
L
A
G
R
Dog
Lupus familis
XP_543382
1925
209302
A1305
E
P
D
T
P
D
P
A
H
P
P
A
P
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
P1365
E
P
E
T
P
E
P
P
K
P
P
V
P
L
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
P141
E
V
E
I
L
Y
N
P
K
N
K
K
H
L
G
Chicken
Gallus gallus
Q5F3P8
2008
223067
T1375
F
P
E
Q
L
M
V
T
K
T
S
I
E
E
E
Frog
Xenopus laevis
Q66J90
1938
216239
L1323
P
E
K
H
T
G
H
L
K
V
T
K
T
L
S
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
D1246
P
P
P
E
T
L
P
D
M
P
V
R
G
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
R1086
K
P
S
F
E
Y
D
R
I
Y
S
D
S
E
E
Honey Bee
Apis mellifera
XP_395451
1406
159180
D852
E
D
N
E
K
I
D
D
K
S
V
D
K
E
Y
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
R953
S
I
Q
S
S
P
E
R
Q
R
D
V
S
S
S
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
K1233
E
E
E
K
V
P
K
K
P
P
P
A
I
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
I759
V
D
N
R
Y
S
M
I
R
D
T
E
E
P
E
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
13.3
0
53.3
N.A.
53.3
N.A.
N.A.
13.3
26.6
6.6
20
N.A.
20
6.6
6.6
26.6
P-Site Similarity:
100
13.3
13.3
66.6
N.A.
60
N.A.
N.A.
13.3
40
20
20
N.A.
26.6
6.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
15
0
8
0
15
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
8
0
0
15
15
15
0
8
8
15
0
0
0
% D
% Glu:
43
15
36
15
8
8
15
0
0
8
0
8
15
22
43
% E
% Phe:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
8
0
0
0
8
0
8
8
8
% G
% His:
0
0
0
8
0
0
8
0
15
0
0
0
8
0
0
% H
% Ile:
0
8
0
8
0
8
0
8
8
0
0
8
8
0
0
% I
% Lys:
8
0
8
8
8
0
8
8
36
0
8
15
8
0
0
% K
% Leu:
0
0
8
0
15
8
0
8
0
0
0
8
0
29
8
% L
% Met:
0
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
8
0
0
8
0
0
0
0
0
% N
% Pro:
15
50
8
15
29
22
22
22
15
36
22
8
29
22
8
% P
% Gln:
0
8
8
8
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
15
15
8
0
8
0
8
8
% R
% Ser:
15
0
8
8
8
15
0
8
0
8
22
0
15
8
22
% S
% Thr:
0
0
0
22
22
0
0
8
0
8
15
0
8
0
0
% T
% Val:
15
8
0
0
8
0
8
0
0
8
22
22
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
15
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _